Intravitreal Ranibizumab in Retinal Pigment Epithelial Detachments
Germany40 participantsStarted 2008-12
Plain-language summary
The purpose of this study is to demonstrate the efficacy of ranibizumab in patients with retinal pigment epithelial detachment secondary to age-related macular degeneration (AMD).
Who can participate
Age range50 Years
SexALL
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Inclusion Criteria:
* patients with age-related macular degeneration and serous pigment epithelial detachment as determined by fluorescein and indocyanine green angiography and optical coherence tomography (OCT)
* patients who have a best-corrected visual acuity (BCVA) score between 73 and 24 ETDRS letters
* patients with pigment epithelial detachment (PED) ≥ 200 µm as determined by OCT
* male or female patients 50 years of age or greater
* patients willing and able to comply with all study procedures
Exclusion Criteria:
* patients with best-corrected visual acuity (BCVA) \< 24 or \>73 letters in the study eye
* patients previously treated by intravitreal injections of steroids or anti-VEGF agents, or patients previously treated by Verteporfin photodynamic therapy or focal laser photocoagulation
* history of uncontrolled glaucoma in the study eye
What they're measuring
1
To investigate the efficacy of ranibizumab in patients with retinal pigment epithelial detachment secondary to age-related macular degeneration