The Effect of HPV Vaccination on Recurrence Rates in HIV Patients With Condylomata

Inclusion Criteria: * ≥18 years of age; * HIV positive status; * CD4 \> 200 and viral RNA \< 400 on anti-retroviral therapy (HAART) or CD4 \> 350 if not on HARRT; * the presence of anal warts that require surgical excision/ablation. Exclusion Criteria: * CD4 \< 200 and/or viral RNA \> 400 on HAART or CD4 \< 350 and not on HAART ; * low burden of anal warts that would not require surgical excision/ablation; * previous vaccinations against HPV or allergic reactions to any vaccine component; * patients who are currently pregnant; * patients with a previous diagnosis of anal cancer; * patients who are incarcerated; * patients who have taken immunomodulators (i.e. interferon, interleukin, corticosteroids, etc.) within the last 90 days; * patients who have had an opportunistic infection in the last 90 days or who have another intercurrent illness that precludes their safe enrollment in this study; * patients who, in the judgment of the investigators, are unlikely to adhere to the protocol, either because of a substance abuse or psychiatric diagnosis, or other factors that would affect compliance; * failure to strictly comply with the vaccination schedule.