The aims of this prospective, randomized study are:
* To assess the effect of clean intermittent catheterization (CIC)
* To investigate if MS patients will have symptom reduction (urgency, frequency, nocturia and incontinence) when using CIC in combination with anticholinergic drugs
* To identify at what volume of Postvoid Residual (PVR) urine, starting CIC improves bladder control and QoL
* To increase the evidence of CIC, and support clinical guidelines of bladder management in MS patients
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Provision of informed consent
* Male and female patients aged 18 years and over
* MS patients that are already currently treated or eligible for treatment with anticholinergic drugs
* Patient with previously confirmed multiple sclerosis according to McDonald Criteria and level of disability less than 6.5 on the Kutzke scale and have been stable for 6 months
* The patient has all or any bladder symptoms; urgency, frequency, incontinence, nocturia, PVR
* The patient has Frequency symptoms \> 8 voiding per 24 h
* The patient has PVR \> 50 ml, measured at two repetitive bladder scan measurements during the screening phase as well as the randomization visit
* Adequate mobility to lower limbs, sufficient hand function and ability to practice CIC at least three times daily
Exclusion Criteria:
* Pregnancy
* Ongoing symptomatic Urinary Tract Infection (UTI) as judged by investigator
* Involvement in the planning and conduct of the study (applies to both Astra Tech staff or staff at the study site)
* The patient practices CIC prior the study
* The patient has undergone a sphincterectomy
* Progressive "Relapsing- remitting MS" as judged by the investigator
* Severe non-compliance to protocol as judged by the investigator and/or Astra Tech
* The patient is participating in other study that might have an impact on the outcome of this, as judged by investigator
* PVR \> 250 ml, measured at two repetitive bladder scan measurements during the screening phase as well …
What they're measuring
1
Percent Change From Baseline in Frequency of Micturition Per Day at 8 Weeks.
Timeframe: Baseline and 8 weeks after randomization.