A/H5N1/LT Dose Ranging Study

Inclusion Criteria: * Healthy adult male or females 18 to 49 years of age (inclusive) * Signed Informed Consent * Women who are not post-menopausal or surgically sterile must have a negative serum or urine pregnancy test at screening and within 24 hours of vaccination with understanding (through informed Consent process) to not become pregnant over the duration of the study, and must agree to employ an effective form of birth control for the duration of the study. Acceptable forms of birth control are: abstinence, hormonal contraceptives (oral, injectable, implant, patch, ring), double-barrier contraceptives (condom or diaphragm, with spermicide) and IUD Exclusion Criteria: * Clinically significant laboratory abnormalities at screening * Abnormalities at physical examination \[as determined by the Toxicity Grading Scale (grade 1-4)\] * Known allergies to any component of the vaccine * Known egg protein allergy * Known allergies to adhesives * Known disturbance of coagulation * Participated in research involving investigational product within 45 days before planned date of vaccination * Donated or received blood or blood products such as plasma within the past 45 days * Received any licensed vaccines within 2 weeks (for inactivated vaccines) or 4 weeks (for live vaccines) prior to planned date of vaccination * Ever received investigational enterotoxigenic E. coli, or LT (R192G) or NasalFlu, Berna Biotech Ltd * Ever received cholera toxin or vaccine (e.g. Orochol, Dukoral) *…