Stopped: Realized there was a design flaw.
This is a study to evaluate the cause of chronic sinus disease. Oral steroids have long been used in the treatment of inflammatory conditions including chronic sinusitis, asthma, and arthritis. However, it is not well known exactly which patients will benefit from steroids when used in the treatment of chronic sinusitis. For some doctors, it is common practice to use these medications prior to planned sinus surgery, to lessen the inflammation and possibly help the healing process. Other doctors feel oral steroids may not be helpful in this way, and there is no conclusive data as to whether this practice has a long term benefit.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Alterations of inflammatory cells, levels of key antibodies and cytokines, and expression of key epithelial genes
Timeframe: Prior to surgery and steroid treatment and day of surgery w/ or w/o having been treated w/ steroids