Trial to Evaluate the Hemostatic Effect of Lyostypt® Versus Surgicel® in Arterial Bypass Anastomosis

Inclusion Criteria: * Patients with an indication for a peripheral vascular reconstruction due to peripheral vascular disease (PVD) including femoro-femoral, femoro-popliteal and femoro-crural reconstructions or the need of a crossover including femoro-femoral or ilaco-femoro reconstruction. * suture hole bleeding of peripheral arterial bypass anastomosis using PTFE graft prosthesis * Written informed consent Exclusion Criteria: * Emergency surgery * Patients with coagulopathy or uremia * Reoperation within one month at the same location * Pregnant and Breastfeeding Women * Known or suspected allergies or hypersensitivity to any of the used devices (e.g. to material of bovine origin) * Severe comorbidity (ASA ≥ 4) * Life expectancy less than 12 months * Current immunosuppressive therapy (more than 40 mg of corticoid per day or ezathioprin) * Chemotherapy within last 4 weeks * Radiotherapy on the treated region within the last 2 months * Severe psychiatric or neurologic diseases * Lack of compliance