Clinical Equivalence of Two Butenafine Hydrochloride 1% Creams in Patients With Interdigital Tinea Pedis

Inclusion Criteria: * Microbiologically confirmed clinical diagnosis of interdigital tinea pedis * If female and of child bearing potential, prepare to abstain from sexual intercourse or use a reliable method of contraception during the study (e.g., condom, intra-uterine device (IUD), oral, transdermal, injected or implanted hormonal contraceptives). * A confirmed clinical diagnosis of interdigital tinea pedis. Lesions are to be predominately interdigital but may extend to other areas of the foot (the non-interdigital lesions must not be hyperkeratotic). * The presence of tinea pedis infection, confirmed by the observation of segmented fungal hyphae during a microscopic potassium hydroxide (KOH) wet mount examination (potassium hydroxide mount preparation). * Identification of an appropriate dermatophyte by culture sent to the central laboratory. The appropriate dermatophytes are Trichophyton rubrum, Trichophyton mentagrophyte or Epidermophyton floccosum. Exclusion Criteria: * Use of any of the following within the indicated timeline: * Oral or injectable steroids * Any oral anti-fungals within 4 weeks of the study start * Use of topical corticosteroids or any other topical antipruritics on the feet within 72 hours of the study start. * Any prescription or over-the-counter (OTC) topical antifungals on the feet within two weeks prior to study entry * Use of any antihistamines within 72 hours of the study start. * Any known hypersensitivity to butenafine or other antifungal …