Trial of Sunitinib for Refractory Malignant Ascites

Inclusion Criteria: * Solid tumor malignancy and failure of at least one biologic or cytotoxic regimen, or the inability to receive standard treatment due to performance status (PS\>2). * Ascites based on paracentesis or CT scan within one month prior to enrollment * Life expectancy \> 3 months * Indwelling paracentesis catheters are permitted, paracentesis is permitted at the investigators discretion * Negative urine pregnancy test for females * All subjects must agree to use birth control * All subjects must abstain from eating grapefruit and grapefruit juice. They must tell their physicians about any changes in their medication including over-the-counter and herbal supplements. Exclusion Criteria: * History of congestive heart failure * Creatinine \> 2.0 * Pregnant or nursing * ALT \> 2.5 times the upper limit of normal * Blood pressure \> 160/90 (antihypertensives permitted) * Gastrointestinal or intra-abdominal hemorrhage within the last 6 months * History of QTc \> 450 milliseconds * Brain metastasis