Recovery From Psychosis in Schizophrenia - The Impact of Cognitive-Behavioral Therapy (NCT00791440) | Clinical Trial Compass
CompletedNot Applicable
Recovery From Psychosis in Schizophrenia - The Impact of Cognitive-Behavioral Therapy
United States34 participantsStarted 2008-11
Plain-language summary
This study examines the impact of Cognitive-Behavior Therapy (CBT) on symptoms, physiological arousal, stressors, and the ways to deal with them in individuals with schizophrenia and related disorders. The primary aim of this study is to investigate the role cognitive coping strategies play in mediating the link between stress, physiological arousal, and psychotic symptoms in individuals with schizophrenia during recovery from psychosis.
Who can participate
Age range18 Years – 50 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Males and females between ages 18-50.
* Have capacity to give informed consent.
* English speaking.
* Have a DSM-IV diagnosis of schizophrenia, or schizoaffective disorder, or schizophreniform disorder.
* Presence of active psychosis as indexed by ratings ≥3 on any hallucinations and delusions items of the Scale for Assessment of Positive Symptoms (SAPS).
Exclusion Criteria:
* Lacks capacity to give informed consent.
* Diagnosis of mental retardation (IQ \< 80).
* Have history of neurological disorders or medical conditions known to seriously affect the brain.
* Have history of cardiac conditions or hypertension; current use of anti-cholinergic, beta-blockers, anti-histamine, or anti-hypertensive medication; abnormalities on ECG.
* Have used street drugs within the past 4 weeks.
What they're measuring
1
Scale for the Assessment of Positive Symptoms (SAPS)
Timeframe: At Baseline and after 10, 20 and 30 weeks