Diaphragmatic Function in Ventilated Patients (NCT00786526) | Clinical Trial Compass
CompletedNot Applicable
Diaphragmatic Function in Ventilated Patients
France55 participantsStarted 2008-03
Plain-language summary
Animal studies showed that controlled mechanical ventilation (CMV) can induce dysfunction of the diaphragm, resulting in an early-onset and progressive decrease in diaphragmatic force-generating capacity, called ventilator-induced diaphragmatic dysfunction (VIDD).
Who can participate
Age range18 Years ā 85 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Invasive mechanical ventilation (tracheally intubated or tracheotomized) less than 48h.Ā·
* Duration of mechanical ventilation for at least 72h.Ā·
* Subject itself or its next of kin has given written informed consent
Exclusion Criteria:
* Patient is less than 18 years or more than 85 years of ageĀ·
* The attending physician refuses to allow enrollmentĀ·
* The patient refuses informed consent
* Next of kin is unavailable or refuses informed consentĀ·
* Pregnant or breast-feeding female.
* A pregnancy test will be performed in all female patients less than 60 years of age.Ā·
* Any contraindication to use cervical magnetic stimulation (mechanical cardiac assist device ā¦).Ā·
* Presence or suspicion of prior diaphragm injury or chronic diseaseĀ·
* Presence or suspicion of a central nervous system (CNS) disorder, including (but not limited to): CNS infarction, bleeding, tumor, or infection