The Pharmacokinetics of 2% TD1414 Cream in Adults With Secondarily Infected Traumatic Lesions (SITL) or Impetigo

Inclusion Criteria: * Ability and willingness to comply with all the study requirements/procedures * Age ≥ 18 and ≤65 years * Primary bullous/non-bullous impetigo or SITL * Patients suffering from primary bullous/non-bullous impetigo must have: * Not more than 10 discrete lesions, and * A total lesional area ≥ 1 cm2 and ≤ 100 cm2, and * Any surrounding erythema must not extend beyond 2 cm from the edge of the lesion, and * Total SIRS score equal to or ≥ 8 * Patients suffering from SITL must have: * A total infected area of the traumatic lesion ≥ 1 cm2 and ≤ 100 cm2, and * Any surrounding erythema must not extend beyond 2 cm from the edge of the lesion, and * Total SIRS score ≥ 8, and * SITL not caused by burns or animal/human bite * Amenable for treatment with topical antibiotic alone * Body Mass Index ≥18 and ≤ 35 kg/m2. Exclusion Criteria: * Immunosuppressed state or other serious systemic disease * Signs and/or symptoms of systemic infection, such as malaise and fever or local adenopathy and fever * Unwillingness to abstain from use of any other topical products including emollients on the lesional area during the study * Systemic treatment with antibacterials or immunosuppressive agents (e.g. corticosteroids) within 2 days before day 1 (inhaled/intranasal steroids may be used) * Topical treatment with antibacterials, immunosuppressive agents (e.g. corticosteroids) or antiseptics (e.g. alcohol, chlorhexidine, hydrogen peroxide, iodine) on the lesional …