UnknownNot Applicable

Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions of the United Kingdom

United Kingdom14,000 participantsStarted 2008-02

Plain-language summary

RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This study is looking at genetic susceptibility to cancer and interactions between genes and the environment in patients with cancer in East Anglia, Trent, or West Midlands of the United Kingdom.

Who can participate

Age range18 Years – 69 Years

SexALL

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DISEASE CHARACTERISTICS: * Diagnosed with bladder cancer, kidney cancer, esophageal cancer, pancreatic cancer, brain cancer, malignant melanoma, or lymphoma within the past 5 years * Identified through the Cancer Research Network OR through the cancer registry serving any of the following geographic regions of the United Kingdom: * East Anglia * West Midlands * Trent PATIENT CHARACTERISTICS: * Identified by the patient's general practitioner as fit to contact for this study * No serious mental illness or retardation PRIOR CONCURRENT THERAPY: * Not specified

What they're measuring

Acquisition of epidemiological information and biological material

Identification of novel cancer susceptibility genes

Estimation of the age and sex-specific risks associated with variants in predisposition genes

Evaluation of interactions between polymorphisms in predisposition genes and potential lifestyle risk factors

Trial details

NCT IDNCT00757614

SponsorCancer Research UK

Sponsor typeOTHER

Study typeOBSERVATIONAL

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