CompletedNot Applicable

The Effect of Granulocyte Colony Stimulating Factor (G-CSF) on Myocardial Function After Acute Anterior Myocardial Infarction, a Prospective Double Blind Randomized Placebo Controlled Study

Iran20 participantsStarted 2007-06

Plain-language summary

The investigators applied G-CSF to patients 2 weeks after acute anterior MI and successful PCI to evaluate the efficacy and safety of G-CSF in improving myocardial function as cytokine which improve inflammation and mobilize stem cells from bone marrow for regeneration of myocardium.

Who can participate

Age range30 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * First anterior myocardial infarction. * Low systolic ventricular function. Exclusion Criteria: * Bleeding tendency * Contraindication to G-CSF * Cardiogenic shock * Hemodynamic instability * Hepatic or renal disease * Multivessel disease

What they're measuring

Ejection fraction

Timeframe: 6 months

Diastolic function(Tei index)

Timeframe: 6 months

Trial details

NCT IDNCT00756756

SponsorShiraz University of Medical Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2007-10

View on ClinicalTrials.gov More Myocardial Infarction trials