AScVS and/ or Prazosin for Scorpion Envenomation (NCT00753064) | Clinical Trial Compass
CompletedPhase 3
AScVS and/ or Prazosin for Scorpion Envenomation
India81 participantsStarted 2006-09
Plain-language summary
The data available for the efficacy of AScVS and prazosin is generated through different trials done in different clinical setting. Hence it was felt worthwhile to confirm the documented efficacy of AScVS and prazosin in terms of time taken for clinical recovery in a clinical trial. Along with this, effects of both the therapies on various biochemical parameters will be recorded and compared with. It was also felt necessary to study the effect of combination on the clinical outcome.
Who can participate
Age range12 Years – 65 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Patients of both sexes, in the age range of 12-65 years
✓. reporting to the PHC/ hospital within 48 hours of scorpion sting and
✓. associated with s/s of scorpion envenomation having composite score between 5 and 21 (as computed based on the criteria below:)
✓. Minimal sweating all over the body, slight nasal secretions
✓. Generalized sweating with rigors and cold extremities.
✓. Gen.profuse sweating,wetting of clothes and cold clammy skin.
✓. 91 - 100
✓. 101 - 120 or \< 70
Exclusion criteria
✕. Composite score less than 5 and greater than 21.
✕. Grade of 5 in any of the criterion
✕. Severe Pulmonary edema with oxygen saturation below 80%.
✕. Severe scorpion envenomation with reporting time more than 2 days
✕. Any other serious medical disease which/treatment of which may confound the results e.g. cardiac diseases, diabetes, renal diseases etc.
✕. Severe anaphylactic reaction to any of the study drugs
What they're measuring
1
Superiority of AScVS and AScVS+Prazosin was confirmed over use of Prazosin alone.