A Trial to Test the Response to Different Vaccination Regimens With an H5N1 Vaccine With AS03 in Adults Aged 18-64

Inclusion Criteria: * A male or female 18-64 years old at the time of the first vaccination. * Written informed consent obtained from the subject. * Good general health as established by medical history and clinical examination before entering into the study. * Access to a consistent means of telephone contact. * Comprehension of the study requirements, ability to comprehend and comply with procedures for collection of short- and long-term safety data, expressed availability for the required study period, and ability and willingness to attend scheduled visits. * Subjects who the investigator believes that they can and will comply with the requirements of the protocol should be enrolled in the study Exclusion Criteria: * Presence of evidence of substance abuse or of neurological or psychiatric diagnoses which, even if clinically stable, are deemed by the investigator to render the potential subject unable/unlikely to provide accurate safety reports. * Diagnosed with cancer, or treatment for cancer, within 3 years. * Persons with a history of cancer who are disease-free without treatment for 3 years or more are eligible. * Persons with a history of histologically-confirmed basal cell carcinoma of the skin successfully treated with local excision only are excepted and may be enrolled, but other histological types of skin cancer are exclusionary. * Women who are disease-free 3 years or more after treatment for breast cancer and receiving long-term prophylactic tamoxifen are ex…