New Medication Treatment for Stimulant Dependence

Inclusion Criteria: * Males and females who have given written informed consent. * Ages 18 years and above and, must weigh at least 40 Kg and no more than 140 Kg. * Good physical health as determined by a complete physical examination, an EKG within normal limits, and laboratory screening tests within acceptable parameters. * Current DSM-IV diagnosis of cocaine dependence. * At least one positive urine drug screen for cocaine at screen or baseline prior to randomization. * The pregnancy test for females at intake must be negative. * Literacy in English and ability to read, understand, and complete the ratings scales and questionnaires accurately, follow instructions, and make use of the behavioral treatments. * Answered an advertisement in the newspaper/radio/television, and expressing a wish to stop using cocaine. * Willing to participate in behavioral treatments for cocaine dependence. Exclusion Criteria: Please contact site for additional information