Study of Preladenant for the Treatment of Antipsychotic Induced Movement Disorders in Participants With Schizophrenia (Study P04628)

Inclusion Criteria: * Males or females \>=18 and \<=65 years old with a body mass index of 17-31 kg/m\^2. * Diagnosed with Diagnostic and Statistical Manual of Mental Disorders, 4th Ed. (DSM-IV) criteria for schizophrenia/schizoaffective (depressive type) disorder with antipsychotic-induced extrapyramidal symptoms (parkinsonism, akathisia, dystonia, or tardive dyskinesia \[TD\]) based on the following ESRS criteria: * parkinsonism, dystonia, or TD - ESRS score \>=2 on 2 items or \>=3 on one item, * akathisia - ESRS score \>=3 on two items, * Has total ESRS score \>8. * Must be receiving neuroleptics at a stable dosage for at least 7 days prior to enrollment. * Clinical laboratory tests, physical exam, and electrocardiogram must be within normal limits or clinically acceptable to the investigator/sponsor (except signs and symptoms of Schizophrenia/Schizoaffective disorder). * Liver function tests must be within normal limits at screening. * Participant screening for drugs with a high potential for abuse must be negative. * Must be free of any clinically significant disease other than schizophrenia/schizoaffective disorder that would interfere with the study evaluations or procedures. * Must have a level of understanding sufficient to communicate with research staff, cooperate with all protocol required tests and examinations, and be able to adhere to protocol restrictions and schedules. * Must be able to understand the nature of the study and must be willing to sign an i…