Assessment of Mechanisms of Improved Wound Healing (NCT00673309) | Clinical Trial Compass
CompletedPhase 2/3
Assessment of Mechanisms of Improved Wound Healing
United States644 participantsStarted 2000-07
Plain-language summary
The purpose of this study is to find ways to improve wound healing and decrease the negative effects of trauma from burn injury.
Who can participate
Age range90 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patient is between 0 and 90 years of age
* Patient 18 years and older consents to participate in study protocol. If patient is not able to consent, consent will be obtained from closest family member or legal guardian. Parental permission will be obtained for patients less than 18 years of age. Assent will be obtained from children 7-17 years of age if child is physically/mentally able to do so.
* greater than 30% TBSA burn requiring at least 1 operation with donor sites for skin grafting
Exclusion Criteria:
* Known history of AIDS, AIDS-related complex, Human Immunodeficiency Virus
* History of cancer within 5 years
* Tuberculosis, arthritis, cirrhosis, hyperlipidemia, bone or endocrine diseases, autoimmune diseases
* Chronic glucocorticoid or non-steroidal anti-inflammatory drug therapy
What they're measuring
1
Decrease Hypermetabolism as Measured by Stable Isotope Infusion Study
Timeframe: Admission to burn unit to 95% wound healing
Trial details
NCT IDNCT00673309
SponsorThe University of Texas Medical Branch, Galveston