A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN)

Inclusion criteria: * 18 years or older * Female subjects are eligible to enter if of non-childbearing potential or not lactating, has a negative pregnancy test and agrees to use a specified highly effective method for avoiding pregnancy * Documented medical diagnosis of Type 1 or 2 diabetes including: * Stable glycemic control for 3 months defined as \<25% change of routine insulin, \<50% change of routine oral anti-diabetic agent dose and HbA1c \< 8%. (HbA1c of 8 to 11% eligible if attempts to improve diabetic control failed) * DPN defined by: * Bilateral reduced or absent reflexes at the ankles, or * Bilateral impaired vibration, pinprick, fine touch or temperature perception in the distal lower extremities And * Persistent distal burning or dull pain in the feet, or * Persistent proximal aching pain in the legs, or * Paroxysmal electric, shooting, stabbing pain, or * Dysasthesias, or * Evoked pain And * history of pain for at least six months and no greater than five years attributed to DPN (refers to duration of pain) * Baseline 24-hour average daily pain intensity score \>4.0 as measured on an 11 point pain intensity numerical rating scale * Provides written informed consent in accordance with all applicable regulatory requirements Exclusion criteria: * Other chronic pain conditions not associated with DPN. However, the subject will not be excluded if: * The pain condition is located at a different region of the body, and * The pain intensity of this condition is not…