A Study Comparing the Efficacy and Safety of Valdecoxib Plus Parecoxib Versus Valdecoxib Plus Placebo for the Treatment of Pain After Coronary Artery Bypass Surgery

Inclusion criteria: * Patients expected to receive in-hospital pain medication for pain after coronary artery bypass graft surgery for at least 3 full days and pain medication over a 10-day period * New York Heart Association Class I to III or cardiac ejection fraction of at least 35% before surgery * Body mass index of less than or equal to 40 kg/m2 and weight of \>55 kg * Patients scheduled to undergo an isolated (bypass grafting only without valve replacement, significant aortic reconstruction, or ventriculoplasty) primary CABG surgery via median sternotomy, using cardiopulmonary bypass Exclusion criteria: * Patient has undergone or is going to have emergency coronary artery bypass graft surgery or surgery without cardiopulmonary bypass procedure * Symptomatic peripheral vascular disease * Heart attack within 48 hours of surgery