Comparison of Corneal Grafts Cultured in Serum-free Versus Corneal Grafts Cultured in Serum Supplemented Culture Media

Inclusion Criteria: * Male and female patients between 50 and 85 years of age * Clinically proven Fuchs corneal dystrophy or secondary decompensation the corneal endothelium (e. g. after surgical intervention in the anterior segment of the eye) * Patient informed consent Exclusion Criteria: * Previous penetrating keratoplasty * Corneal neovascularisation * Pathologic changes in the anterior segment of the eye (anterior / posterior synechiae, uveitis) * Glaucoma * Aphakia * Infectious diseases of the cornea * Neurodermitis * Participation of the patient in another clinical trial within the last four weeks that precede the recruitment * The patient is unlikely to comply with the requirements of the protocol * Previous or current abuse of medications, narcotics or alcohol * Pregnancy