StrataGraft™ Skin Tissue (Human Donor Skin) In The Surgical Management Of Complex Skin Defects

Inclusion Criteria: * Patients aged greater than 18 yrs. * Patients with complex skin defects requiring sequential debridement under anesthesia with temporary biological dressing (allogeneic grafting) prior to autografting * Full-thickness skin defects * Informed consent Exclusion Criteria: * Prisoners * Pregnant (positive urinary pregnancy in women of child-bearing potential at Visit#1) or lactating females * Immunosuppressive therapy * Infection with Human Immunodeficiency Virus * Venous stasis ulcers of the lower leg * Diabetic foot ulcers * Donor site wounds * Wounds of less than 5% body surface area * Wounds of the hands, face, and feet (although such wound surface areas can be counted toward total injured BSA) * Prior entry into this study * Expected survival of less than 3 months * Concomitant processes sustained contemporaneously with the dermal injury (e.g., inhalational injury requiring ventilation, electrical injury with cardiac damage or arrhythmia, sepsis, other serious or unstabilized organ damage from trauma, etc.) * Use of an investigational agent within 30 days * Active malignancy * Clinical evidence of malnutrition * Clinically significant renal, hepatic, cardiac, pulmonary, or neurological impairments