Efficacy of YKP3089 in Patients With Photosensitive Epilepsy

Inclusion Criteria: * Male or female age 18-60 years. * A diagnosis and history of epilepsy for which patients are on 0-2 concomitant antiepileptic drugs. * If the patient is taking two concomitant medications, the second drug must be levetiracetam, gabapentin or pregabalin. * A reproducible IPS-induced photo-paroxysmal response (PPR) on EEG of at least 3 points on a frequency assessment scale (See Section 6.16) in at least one eye condition and no change of more than 3 frequencies in 2 repeated measurements recorded over the 2 months prior to study entry in at least one eye condition. * Patients in otherwise good health (with the exception of epilepsy), as determined by the PI via the medical history, a physical examination and screening laboratory investigations. * A body mass index (BMI) between 18 and 35. * Able and willing to provide written informed consent to participate in the study in accordance with the ICH, GCP guidelines. Exclusion Criteria: * A history of non epileptic seizures (e.g. metabolic, structural or pseudo-seizures). * Women who are pregnant or lactating. * Women of reproductive potential who do not agree to use effective birth-control methods. * Patients taking medications that are known substrates of CYP2B6 and CYP2C19 including but not limited to phenytoin, Phenobarbital, omeprazole, fluvoxamine and efavirenz. * Any clinically significant laboratory abnormality which, in the opinion of the investigator, will exclude the patient from the study. * An…