Dose-Ranging Clinical Trial of Topical Creams Containing API 31510 for the Treatment of Superficial Basal Cell Carcinoma

Inclusion Criteria: * Male or female adults ≥ 18 years of age * Primary, histologically confirmed sBCC with a minimum area of 0.5 cm2 and with a maximum diameter of 2.0 cm target sBCC lesion suitable for excision * Histological diagnosis made no more than 4 weeks prior to the screening visit * Histological biopsy removed 25% or less of the target lesion * No other dermatological disease in the sBCC target site or surrounding area * Willing to refrain from using non-approved lotions or creams on the target site and surrounding area during the treatment period. Willing to refrain from washing the treated area for at least 8 hours following the application of study medication * Willing to refrain from exposure to direct sunlight or ultraviolet light and to avoid the use of tanning parlors for the duration of the study * Laboratory values for the tests listed in the Study Schedule on page 2 within the reference ranges as defined by the central laboratory, or "out of range" test results that are clinically acceptable to the investigator. * Ability to follow study instructions and likely to complete all study requirements * Written informed consent obtained, including consent for tissue to be examined and stored by the central dermatopathologist * Written consent to allow photographs of the target sBCC lesion to be used as part of the study data * For females of childbearing potential, a negative pregnancy test at screening and using an acceptable form of birth control (oral/impla…