The Zeaxanthin and Visual Function Study (NCT00564902) | Clinical Trial Compass
CompletedNot Applicable
The Zeaxanthin and Visual Function Study
United States60 participantsStarted 2007-11
Plain-language summary
To evaluate if supplementation of zeaxanthin (with or without Lutein) is beneficial to patients with early and moderate Atrophic Age Related Macular Degeneration.
Who can participate
Age range45 Years ā 90 Years
SexALL
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Inclusion Criteria:
* diagnosis of atrophic AMD (ICD9 362.51) by stereo bio-ophthalmoscopy and at least one vision degrading visual-psychophysical abnormality associated with AMD in one or both eyes.
* clear non-lenticular ocular media (cornea, aqueous and vitreous)
* free of advanced glaucoma and diabetes or any other ocular or systemic disease that could affect central or parafoveal macula visual function
Exclusion Criteria:
* high risk retinal characteristics for advanced AMD or advanced AMD for which existing medical / surgical options are available
* presence of ophthalmologically significant active exudative, AMD pathology by fluorescein angiography but also a single large drusen, \>15, multiple intermediate drusen, parafoveal geographic atrophy or loss of vision in one eye due to advanced AMD
* recent (within 6 months) cataract or retinal surgery
* taking photosensitizing drugs such as phenothiazines and chloroquine
* having taken lutein or zeaxanthin supplements within the past six months.