Safety and Effects of SLx-2101 Taken for up to 14 Days on Blood Pressure in Patients With Hypertension

Inclusion Criteria: * Male or females between 18 and 80 years, inclusive * Moderate to severe hypertension * Body weight within a body mass index range of 18 - 32 kg/m2 Exclusion Criteria: * Subject is receiving more than four antihypertensive agents * History of drug abuse * Exposure to a new chemical entity within 3 months prior to the first day of dosing