Ranibizumab Therapy for Non-arteritic Ischemic Optic Neuropathy

Inclusion Criteria: * provide written informed consent * 21 years of age or older * new onset, within 14 days, of ischemia and vision loss * Best Corrected Visual Acuity (BCVA) 20/40 or worse Exclusion Criteria: * pregnancy or lactation * proliferative diabetic retinopathy, * diabetic macular edema, * uveitis, * history of ocular trauma, * severe glaucoma, * age-related macular degeneration. * prior or concomitant treatment of oral steroids within 30 days, * participation in any studies of investigational drugs within 30 days, * participation in a ranibizumab clinical trial or, * prior treatment intravitreally or intravenously of Avastin or steroids.