Ceftobiprole in the Treatment of Hospitalized Patients With Staphylococcus Aureus Bacteremia (NCT00505258) | Clinical Trial Compass
WithdrawnPhase 2
Ceftobiprole in the Treatment of Hospitalized Patients With Staphylococcus Aureus Bacteremia
Stopped: The study was withdrawn due to lack of an appropriate patient population.
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Plain-language summary
The purpose of this study is to assess the safety and efficacy of ceftobiprole versus a comparator in hospitalized patients with bacteremia.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Hospitalized patients with signs and symptoms suggestive of systemic staphylococcal infection as defined in the protocol
* Female patients must be postmenopausal (for at least 1 year), surgically sterile or practicing an effective method of birth control, male partner sterilization or, at the discretion of the investigator, abstinence, before entry and throughout the study and have a negative urine pregnancy test (confirmed with a negative serum pregnancy test) at screening.
Exclusion Criteria:
* Female patients who are pregnant or lactating
* Known or suspected hypersensitivity to beta-lactam antibiotics or any other study medications
* Receipt of vancomycin or other antistaphylococcal drug for \> 2 calendar days prior to initiation of study drug
* Diagnosis of a catheter-related GPC-cl bacteremia at the time of study enrollment
* Clinical findings of left-sided endocarditis prior to enrollment or any time during study participation
* Requirement for surgery during the seven days of study therapy administration with the exception of surgery required to manage a complication of S. aureus bacteremia
What they're measuring
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To determine the effect of ceftobiprole on the time to bloodstream clearance of methicillin-resistant Staphylococcus aureus and methicillin-susceptible Staphylococcus aureus (MSSA) in treated bacteremic patients.