Ranibizumab to Treat Type 2 Idiopathic Macular Telangiectasia (RAMA-Trial) (NCT00504400) | Clinical Trial Compass
CompletedPhase 2
Ranibizumab to Treat Type 2 Idiopathic Macular Telangiectasia (RAMA-Trial)
Germany10 participantsStarted 2007-08
Plain-language summary
The purpose of this study is to investigate if a new drug called ranibizumab is effective to treat a rare bilateral disease of the macula: type 2 idiopathic macular telangiectasia (type 2 IMT). 10 patients will receive monthly injections of the drug into one eye over a period of one year.
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* diagnosis of type 2 idiopathic macular telangiectasia
* minimum of 18 years
* patient must be able to follow protocol
* written informed consent
* best corrected visual acuity between 20/200 - 20/32 in the treated eye
Exclusion Criteria:
* patients who do not fulfill the inclusion criteria
* patients with other retinal vascular disease such as diabetic retinopathy or venous occlusive diseases
* ocular surgery 3 months before study enrollment
* history of uncontrolled glaucoma
* active intraocular inflammation or inflammation of the ocular adnexa
* subfoveal fibrosis in the study eye
* inability to follow study protocol
* major surgery one month before study enrollment
* history of severe cardiovascular disease or history of stroke 6 months before study enrollment
* allergies against substances or components of the study medication
* low anticipated compliance
* patients who participate(d) in clinical trials simultaneously or within the last 60 days
* pregnancy, lactation, women that may become pregnant and don't use safe contraception
* chronic alcohol- or drug abuse within the last year
* lacking legal competence or language ability
* neurologic diseases such as multiple sclerosis
* need of concomitant medication that is not allowed in combination with ranibizumab
* previous intravitreal therapy with anti-angiogenic substances in the study eye within the last 6 months