PTA and Drug Eluting Stents for Infrapopliteal Lesions in Critical Limb Ischemia

Inclusion Criteria: * Written informed consent * Age \> 18 years * If female patient with child bearing potential, patient may not be pregnant at the study entry and must utilize reliable birth control for the duration of her participation into the study * Patient is willing and able to comply with the specified follow-up evaluation * Critical Limb Ischaemia, this is Fontaine stage III (ischaemic rest pain) and IV (ischaemic ulcers or gangrene) or Rutherford category 4 (ischaemic rest pain), 5 (minor tissue loss) or 6 (major tissue loss) * Stenotic (\>50% luminal loss) or occluded infrapopliteal artery, including the tibiofibular trunk, the anterior tibial artery, the posterior tibial artery and the peroneal artery, with a lesion length ≤ 60 mm * Artery to be treated with a diameter more tham or equal to 2mm and less than or equal to 4mm * Patent common iliac, external iliac, superficial femoral and popliteal artery on the ipsilateral side prior to randomisation, possibly after treatment during the same session * At least one patent crural (anterior tibial, posterior tibial or peroneal) artery with expected unobstructed runoff to ankle level after treatment Exclusion Criteria: * Acute limb ischaemia * Subacute limb ischaemia which requires thrombolysis as first treatment modality * Active bleeding or bleeding diathesis * Recent (less than 3 months) hemorrhagic stroke or other any other CNS abnormality with increased risk of haemorrhage, such as intracranial neoplasm, arter…