MiMi: A Randomized Trial of Mifepristone and Misoprostol for Treatment of Early Pregnancy Failure

Inclusion Criteria: * Age \>18yrs, able to read and write English * Intrauterine gestations with anembryonic sac between 10 and 45mm or * 10-15mm sac with no growth in three days or other radiologic signs of abnormal pregnancy such as irregular sac or debris within the gestational sac * An embryonic pole \<30mm with no cardiac activity Exclusion Criteria: * Intrauterine gestations with CRL \<5mm or \>30mm without cardiac activity * Incomplete abortion as defined as open cervix and large amount of cramping/bleeding * Hemodynamic instability and/or heavy vaginal bleeding * Hemoglobin less than or equal to 8 * Inability to follow-up (ie, lack of transportation or access to telephone) * Bleeding disorder or taking anticoagulants * Prior medical or surgical treatment of the current pregnancy * Obvious Infection * Active Lactation * Allergy to mifepristone or misoprostol * Chronic corticosteroid use * Severe gastrointestinal disease (e.g inflammatory bowel disease, severe gastritis)