Effects of Mycophenolate Mofetil (MMF) On Anti-HLA (Human Leukocyte Antigen)Antibody Levels In Patients Awaiting Cadaveric Renal Transplant.

Inclusion Criteria: * Persons on the kidney transplant waiting list who are currently receiving hemodialysis * Age range 18 - 75 * Outpatient status * Patients with a PRA over 50% for over 6 months * Patients with updated immunizations for tetanus, influenza, hepatitis B, pneumococcus * Patients with a PPD (purified protein derivative) test within the last 6 months. If subject has a prior history of TB (tuberculosis) or positive PPD, documentation of adequate treatment is required. * Women who are of childbearing potential must have a negative serum pregnancy test prior to being enrolled in the study and agree to use a medically acceptable method of contraception throughout the study. Exclusion Criteria: * Active infection * History of multiple recurrent infections defined as more than 3 urinary tract infections, 2 episodes of pneumonia or 3 episodes of otitis/sinusitis in one year, or more than two dialysis line or peritoneal infections within one year. Infection with HCV (hepatitis C virus) or HBV (hepatitis B virus) or HIV (human immunodeficiency virus). * Lack of documentation of PPD testing * Lack of documentation of treatment of a positive PPD * Pregnant or breast-feeding * Baseline leukopenia, WBC \< 4.0 * Thrombocytopenia (platelet count \< 130) or difficult to treat anemia, HCT chronically \< 32 on intravenous iron and EPO (erythropoietin) therapy * Transfusion within 6 months