A Clinical Trial Comparing Laser TURP With and Without Dutasteride.

Inclusion Criteria: * The patient is a male at least 50 years of age. * The patient's peak urinary flow rate is at least 4 ml/sec, but not greater than 15 ml/sec, and the voided volume is at least 125 ml. * Prostate volume must be greater than 30 grams * The AUA-SI is greater than or equal to 9. * Patient must be scheduled for a Laser TURP or eligible to be scheduled for Laser TURP * Patient must be able to complete the study requirements prior to the scheduled laser TURP. * The patient has signed the informed consent prior to the performance of any study procedures. Exclusion Criteria: * The patient has had any prior surgical intervention for BPH. * The patient is receiving any intervention for prostate disease (either medical or surgical) or is presently enrolled in any study protocol. * The patient has had a previous hypersensitivity, idiosyncrasy, or clinically suspected drug reaction to dutasteride. * The patient has taken an alpha-1 blocker within 1 month of randomization. * The patient has taken finasteride or dutasteride within 3 months of randomization. * The patient has taken phenylephrine, pseudoephedrine, imipramine, and an anticholinergic or cholinergic medication within 4 weeks of the screening visit. * The patient has taken an estrogen, androgen, or any drug producing androgen suppression, or anabolic steroids. * The patient has an inability to urinate. * The patient has clinically significant renal or hepatic impairment (i.e., creatinine greater than 2.0 mg…