Iodine I 131 in Treating Patients With Thyroid Cancer (NCT00416949) | Clinical Trial Compass
TerminatedNot Applicable
Iodine I 131 in Treating Patients With Thyroid Cancer
Stopped: Study was terminated due to loss of funding.
United States9 participantsStarted 2006-04
Plain-language summary
RATIONALE: Radioactive iodine kills thyroid cancer cells by giving off radiation.
PURPOSE: This clinical trial is studying the side effects, best dose, and how well iodine I 131 works in treating patients with thyroid cancer.
Who can participate
Age range18 Years – 100 Years
SexALL
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DISEASE CHARACTERISTICS:
* Diagnosis of thyroid cancer
* Measurable disease by CT scan or nuclear medicine imaging
* Eligible, by standard of care criteria, for iodine I 131 therapy
PATIENT CHARACTERISTICS:
* Not pregnant or nursing
* Negative pregnancy test
* Fertile patients must use effective non-barrier method contraception (e.g., combined or progesterone-only oral contraceptive pill, intrauterine device, depot progesterone, or stable relationship with a partner who has had a vasectomy)
* No other malignancy within the past 5 years except squamous cell or basal cell carcinoma of the skin
* No nonthyroidal conditions known to affect iodine I 131 uptake (e.g., New York Heart Association class III or IV congestive heart failure or renal failure)
* No alcoholism or drug abuse within the past 2 years
* No severe emotional, behavioral, or psychiatric problems that would preclude study compliance (e.g., severe claustrophobia)
PRIOR CONCURRENT THERAPY:
* No intravenous water-soluble radiographic contrast within the past 4 weeks
* No iodinated contrast agent within the past 3 months
* No concurrent drugs that may affect thyroid or renal function (e.g., renal drugs, lithium, amiodarone, other iodine-containing medication, or corticosteroids)
* No other concurrent investigational drugs
What they're measuring
1
Tumor Absorbed Dose
Timeframe: up to 4 years
Trial details
NCT IDNCT00416949
SponsorSidney Kimmel Comprehensive Cancer Center at Johns Hopkins