Improving Adherence to Oral Antipsychotic Medications in People With Schizophrenia

Inclusion Criteria: * Diagnosis of schizophrenia or schizoaffective disorder according to DSM-IV criteria, as determined on the basis of the Structured Clinical Interview for Diagnosis (SCID-P) * Receiving treatment with an oral atypical antipsychotic medication other than clozapine (e.g., risperidone, olanzapine, quetiapine, aripiprazole, ziprasidone, or others as they are FDA approved) * Assumes some responsibility for taking own medications * Able to provide evidence of a stable living environment (e.g., individual apartment, family home, or board and care facility) within 3 months prior to study entry and no plans to move in the next year * Intact visual and auditory ability as determined by a computerized screening battery * Ability to read at the 5th grade level or higher based upon score on the Wide Range Achievement Test (WRAT) * Able to understand and complete rating scales and neuropsychological testing * Working telephone present in the home Exclusion Criteria: * History of significant head trauma, seizure disorder, or mental retardation * Alcohol or drug abuse or dependence within 3 months prior to study entry * Currently being treated by an assertive community treatment (ACT) team * History of violence within 1 year prior to study entry * Any hospitalizations within 3 months prior to study entry