Study to Determine if Taking OTC Non-Steroidal Anti-Inflammatory Affects Eye Pressure in Patients… (NCT00402493) | Clinical Trial Compass
CompletedNot Applicable
Study to Determine if Taking OTC Non-Steroidal Anti-Inflammatory Affects Eye Pressure in Patients Using Glaucoma Drops
United States51 participantsStarted 2006-12
Plain-language summary
The Purpose of This Study is to Determine if Taking an Over the Counter Non-Steroidal Anti-Inflammatory(Ibuprofen)has an Effect on Eye Pressure in Patients using Brimonidine(Alphagan)and Latanoprost(Xalatan) eye drops.
Who can participate
Age range21 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients with bilateral or unilateral primary open angle glaucoma or ocular hypertension
* An IOP in each eye of greater than 22mm HG after washout of IOP lowering medications
* No worse than 20/200 best corrected visual acuity
* Normal appearing or non-occludable anterior chamber angles
* Discontinuation of current POAG or OH medications before participation in the study.
* Written Informed Consent
Exclusion Criteria:
* Use of any other ocular medications
* Previous ocular surgery or laser therapy within the last three months.
* Systemic treatment with any adrenergic agonist or antagonist, corticosteroid or nonsteroidal anti-inflammatory agents(low dose apsirin will be accepted if dose remains the same for entire study period).
* An age of less than 21,of child bearing age and currently pregnant, considering pregnancy or a nursing mother.
* A history of medical noncompliance or unreliability.
* Presence of uncontrolled hypertension, cardiac arrhythmia, cerebrovascular accident, nasal polyps, bleeding diathesis, peptic ulcer disease, gastritis or known intolerance, contraindication or allergy to any drugs used in the study.
* Lactose Intolerance.