CompletedNot Applicable

Environmental Exposures, Genetics, and Exhaled Nitric Oxide in Pediatric Asthma

United States225 participantsStarted 2006-07

Plain-language summary

Asthma is one of the most common childhood diseases. It is chronic and often severely disabling. The amount of nitric oxide that is exhaled while breathing increases with airway inflammation, a symptom of asthma. This study will examine the results from a previous study, the Cincinnati Asthma Prevention (CAP) study, to evaluate the effects of environmental and genetic factors on exhaled nitric oxide (eNO) levels and to determine the relationship between eNO and asthma severity.

Who can participate

Age range6 Years – 12 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Participated in the Cincinnati Asthma Prevention Study * Diagnosis of asthma * Lives with someone that smokes at least 5 cigarettes a day Exclusion Criteria: * No additional neuromuscular or respiratory disorder that may interfere with safe participation in the parent study * Does not have electricity * Plans to move within 1 year of entry into the parent study

What they're measuring

Effects of environmental and genetic factors on exhaled nitric oxide (eNO) levels and the relationship between eNO and asthma severity

Timeframe: Measured through the use of data previously collected in the Cincinnati Asthma Prevention (CAP) study

Trial details

NCT IDNCT00395096

SponsorChildren's Hospital Medical Center, Cincinnati

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2008-06

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