Use of Recombinant Human Lactoferrin in Long-Term Care Patients With Feeding Tubes With Clostridium Difficile.

Inclusion Criteria: * Patients in long-term care facility, Ventilator Rehabilitation Unit (VRU) (Plaza) at the John Burton Care Center of the Johns Hopkins Bayview Medical Center. * Nutrition via gastrostomy, naso-gastric or jejunostomy enteral feeding system. * Patients with supplemental oral intake, but primary nutrition via gastrostomy/jejunostomy tube. * Patients with colostomies are also allowed * Not currently on antibiotic therapy and no antibiotics within 10 days. * Patient is negative for Clostridium difficile antigen in screen * Patient, guardian or health care agent willing to give informed consent. Exclusion Criteria: * Patients who will only receive vancomycin, linezolid, or metronidazole as the antibiotic treatment, not broad spectrum antibiotics. All other antibiotics will qualify. * Patients with illeostomies. * Patients who have signs or symptoms of C. difficile infection; such as diarrhea (two or more liquid stools in a 24-hour period) and elevated WBC (more than 15,000/mm3). * Known allergy to rice or rice products.