Effects of an Alternative Treatment for Military Sexual Trauma on PTSD Symptoms, Neurosteroids an… (NCT00374738) | Clinical Trial Compass
CompletedNot Applicable
Effects of an Alternative Treatment for Military Sexual Trauma on PTSD Symptoms, Neurosteroids and Brain Function
United States34 participantsStarted 2006-11
Plain-language summary
Our specific aims are:
1. To examine the efficacy of GIFT in improving MST-related clinical outcomes in women veterans
2. To examine the effects of GIFT on fronto-limbic brain function and
3. To examine the effects of GIFT on levels of neuroactive steroid associated with PTSD.
Who can participate
Age range18 Years – 65 Years
SexFEMALE
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 18-65
* Status as a woman veteran
* Receives care at the Durham VAMC
* History of MST
* DSM-IV diagnosis of PTSD, confirmed by CAPS interview
* Able to participate in a research interview in English
* Regular telephone access
Exclusion Criteria:
* Current diagnosis of organic or psychotic mental disorder
* Suicidality or parasuicidality
* Ongoing family violence
* Alcohol or drug dependence within previous 3 months
* Enrolled in cognitive-behavioral/exposure-based therapy during study period.
* Supportive therapy and psychiatric medications (if stabilized at least 3 months prior to enrollment) are acceptable.
* An uncontrolled medical condition
Exclusion Criteria for the fMRI only:
* Foreign metallic objects or implanted devices in the body incompatible with MRI
* Positive pregnancy test as determined by serum ß-HCG level
* Claustrophobia
* CNS neoplasms or neurological conditions such as Parkinson's Disease, Huntington's Chorea, demyelinating diseases, seizures, hydrocephalus, etc.