Efficacy of Topical Cyclosporin for Ocular Rosacea (NCT00348335) | Clinical Trial Compass
CompletedPhase 4
Efficacy of Topical Cyclosporin for Ocular Rosacea
United States35 participantsStarted 2006-06
Plain-language summary
The purpose of this study is to determine whether Restasis (topical cyclosporin) is effective in the treatment of ocular rosacea
Who can participate
Age range18 Years – 65 Years
SexALL
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Inclusion Criteria:
* Patient at least 18 years old, but younger than 65
* Diagnosis of acne rosacea
* Active ocular rosacea based on lid findings of meibomian gland dysfunction with lid telangiectasia and hyperemia of at least 2+
* Schirmers test of greater than 5mm in at least 1 eye
* If patient currently using lid hygiene must maintain regimen during study
* Stop oral antibiotics at least 4 weeks prior
Exclusion Criteria:
* Use of topical cyclosporin within last 90 days
* Visual acuity of 20/100 or better in both eyes
* Pregnant or lactating females
* Active ocular infection
* Scarring of central cornea
* Eyelid defects,abnormal lid positioning or lagophthalmos
* Flax seed or Fish oil supplements within last 30 days