This is a randomized, double-blind, placebo-controlled, dose-escalation, Phase 1, multi-center study to evaluate the safety, tolerability, immunogenicity, and viral shedding of MEDI-534 in healthy children 1-9 years of age who are seropositive for respiratory syncytial virus (RSV) and parainfluenza virus type 3 (PIV3) at screening.
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To describe the safety and tolerability of 1-9 year old RSV and PIV3 seropositive children
Timeframe: Day 28
Reactogenicity evaluations (REs) from administration of study vaccine through 28 days post-dosing
Timeframe: Day 28 post final vaccination
Adverse events (AEs) from administration of study vaccine through 28 post-dosing
Timeframe: Day 28 post final vaccination
Serious adverse events (SAEs) from administration of study vaccine through 28 days post-dosing
Timeframe: Day 180