AZD2171 and Standard Combination Chemotherapy in Advanced Non-Small Cell Lung Cancer or Colorectal Cancer

DISEASE CHARACTERISTICS: * Histologically or cytologically confirmed diagnosis of 1 of the following: * Non-small cell lung cancer (NSCLC), meeting 1 of the following criteria: * Stage IIIB disease * No pleural effusion and not a candidate for a combined modality treatment * Stage IV disease * Local or metastatic failure after surgery and/or radiotherapy * Colorectal cancer (CRC) * Advanced and/or metastatic disease * Suitable for first-line therapy with oxaliplatin, leucovorin calcium, and fluorouracil (FOLFOX-6) * Clinically or radiologically documented disease * No tumor marker elevation as sole evidence of disease * No necrotic/hemorrhagic metastases or tumor * No untreated brain or meningeal metastases * Previously treated, radiologic or clinical evidence of stable brain metastases allowed provided disease is asymptomatic and corticosteroids are not required PATIENT CHARACTERISTICS: * ECOG performance status 0-2 * Hemoglobin normal * Absolute granulocyte count ≥ 1,500/mm³ * Platelet count ≥ 100,000/mm³ * Creatinine ≤ 1.5 times upper limit of normal (ULN) OR creatinine clearance ≥ 50 mL/min * Bilirubin ≤ 1.5 times ULN * AST or ALT ≤ 2 times ULN (5 times ULN if liver involvement) * Proteinuria ≤ grade 1 * Not pregnant or nursing * Negative pregnancy test * Fertile patients must use effective contraception * No history of other malignancies except adequately treated nonmelanoma skin cancer or other solid tumors curatively treated w…