3-year Study of Menostar Versus Evista to Prevent Osteoporosis in Post-menopausal Women

Inclusion Criteria: * Last (regular) menstrual period more than 5 years ago * Relative good state of health * Intact, normal uterus Exclusion Criteria: * Bone and musculoskeletal diseases * Clinically significant vertebral fracture within the last 12 months * Pre-existing cardiovascular disease (e.g. uncontrolled high/low blood pressure, stroke, thromboembolic event etc) * Uncontrolled diabetes mellitus (or treated with insulin) * Uncontrolled thyroid disorders * Relevant renal disorder or significant liver dysfunction (including cholestasis) * History of alcohol or drug abuse * History of immobilization of more than 2 months in the last 6 months * Smoking of more than 10 cigarettes per day * Unexplained uterine bleeding * Known or suspected malignant or premalignant disease (e.g. cancer of breast or uterus, melanoma)