The Effect of Fatty Acid Composition on Energy Intake and Satiety (NCT00242021) | Clinical Trial Compass
CompletedNot Applicable
The Effect of Fatty Acid Composition on Energy Intake and Satiety
Netherlands20 participantsStarted 2005-10
Plain-language summary
The objective of the study is to investigate the effect of fatty acid composition of a fat supplement:
1. acutely (after single intake) on subjective and objective measurements of hunger, satiety and wellness, on energy intake, and postprandial hormonal changes;
2. in the long-term (after one week) on (regulators of) fat tissue metabolism.
Who can participate
Age range18 Years – 60 Years
SexMALE
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Inclusion criteria
✓. Healthy as assessed by the health and lifestyle questionnaire, physical examination and results of the pre-study laboratory tests;
✓. Males aged between 18 - 60 years at Day 01 of the study;
✓. Normal weight subjects and overweight/obese subjects, Body Mass Index (BMI) will be at least two units different between the heaviest normal weight and the lightest overweight subject, the largest contrast between groups will be aimed at, e.g normal weight BMI between 18 and 25 kg/m2 and overweight/obese BMI between 27.5-35 kg/m2;
✓. Regular Dutch eating habits as assessed by P6468 F02 and used to breakfast consumption;
✓. Non restrained eater, defined as a score of \< 2.5 in lean and \<3.25 in obese men on the Dutch Eating Behaviour Questionnaire;
✓. Appropriate veins for blood sampling/cannula insertion according to TNO;
✓. Voluntary participation;
✓. Having given written informed consent;
Exclusion criteria
✕. Participation in any clinical trial including blood sampling and/or administration of substances up to 90 days before Day 01 of this study;
✕. Participation in any non-invasive clinical trial up to 30 days before Day 01 of this study, including no blood sampling and/or oral, intravenous, inhalatory administration of substances;
✕. Having a history of medical or surgical events that may significantly affect the study outcome, including any psychiatric history, and metabolic or endocrine disease, or any gastro-intestinal disorder or hypertension;
What they're measuring
1
Subjective and objective measurements of hunger, satiety and wellness, on energy intake, and postprandial hormonal changes