CompletedNot Applicable

LOMA: Long-Term Management of Asthma

Canada112 participantsStarted 1999-09

Plain-language summary

The purpose of this study was to determine whether the use of induced sputum cell counts could guide treatment of asthma more effectively than the use of symptoms and breathing tests. The main outcomes where the time to the first exacerbation and the number of exacerbations.

Who can participate

Age range18 Years – 70 Years

SexALL

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Inclusion criteria

✓. History of asthma for at least one year,confirmed objectively.
✓. New or previously reviewed patients where the minimal treatment requirements have not been established within the last six months.

Exclusion criteria

✕. Smokers or ex-smokers for less than 6 months with a smoking history of more than 10 pack years.
✕. Other pulmonary co-morbidity (other than mild or moderate chronic airflow limitation).
✕. Subjects having a co-existing illness that precludes them from the study.
✕. Inability to give informed consent due to mental or legal reasons.
✕. Pregnancy or lactation.
✕. Known non-compliance with medications.

What they're measuring

Relative risk reduction for the occurence of the first exacerbation and the length of time without exacerbation during Phase 2 of the study.

Trial details

NCT IDNCT00182481

SponsorHamilton Health Sciences Corporation

Sponsor typeOTHER

Study typeINTERVENTIONAL

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