Capecitabine in Women With Operable Breast Cancer

Inclusion Criteria: * Histological confirmation of primary invasive breast cancer * Stage I-III operable breast cancer. * Primary tumor must be greater than or equal to 2cm by radiographic imaging or palpitation * Women greater than 18 years of age * ECOG performance status 0-1 * WBC \> 4000/mm3 * Platelet count \> 100,000/mm3 * SGOT \< 2x ULN * Calculated creatinine clearance \> 50ml/min Exclusion Criteria: * Evidence of metastatic (stage IV) cancer on physical exam or any diagnostic study. * Pregnant or breast-feeding women * Inflammatory breast cancer * HER2 positive disease * History of hypersensitivity to a 5-FU or known dihydropyrimidine dehydrogenase (DPD) deficiency * Uncontrolled intercurrent illness * Prior history of breast cancer are ineligible except: diagnosed at least 2 years ago; present cancer is not in previously irradiated breast; no prior chemotherapy in the past 5 years; no prior high-dose chemotherapy with stem cell or bone marrow transplant. * Excisional biopsy performed prior to enrollment * Uncontrolled coagulopathy * Lack of physical integrity of the upper gastrointestinal tract or malabsorption syndrome.