This study is evaluating the safety and immunogenicity of Hib-MenCY-TT vaccine compared to control groups receiving licensed Hib or MenC conjugate vaccines, each administered at 2, 4, 6, and 12 to 15 months of age. Co-administration with live, attenuated measles, mumps, and rubella combination vaccine; and with live, attenuated varicella vaccine will be assessed with administration of the booster dose. The Protocol Posting has been updated in order to comply with the FDA Amendment Act, September 2007.
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Number of Subjects With Anti-polyribosyl-ribitol-phosphate (Anti-PRP) Concentration Greater Than or Equal to 1.0 Microgram Per Milliliter (µg/mL)
Timeframe: One month after the 3-dose primary vaccination course
Number of Subjects With Meningococcal Polysaccharide C Serum Bactericidal Activity/Assay Using Baby Rabbit Complement (rSBA-MenC) Titer Greater Than or Equal to 1:128
Timeframe: One month after the 3-dose primary vaccination course
Number of Subjects Seroconverted for Anti-measles Antibodies
Timeframe: 42 days after the fourth dose vaccination
Number of Subjects Seroconverted for Anti-mumps Antibodies
Timeframe: 42 days after the fourth dose vaccination
Number of Subjects With an Anti-rubella Seroresponse
Timeframe: 42 days after the fourth dose vaccination
Number of Subjects Seroconverted for Anti-varicella Antibodies
Timeframe: 42 days after the fourth dose vaccination