CompletedPhase 3

Efficacy of Elidel Cream on Erosive Oral Lichen Planus

Germany20 participantsStarted 2004-06

Plain-language summary

The purpose of this study is to investigate whether topical applied pimecrolimus will lead to improvement of erosive oral lichen planus. This effect will be monitored by reduction of erosive mucosal area and reduction of patient's pain symptoms.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Clinically and histologically confirmed diagnosis of erosive oral lichen planus * Spontaneous or meal related oral pain * No topical therapy 2 weeks prior to study start * No systemic therapy 4 weeks prior to study start * Signed informed consent Exclusion Criteria: * Pregnant or breast-feeding women * Known allergy to macrolide antibiotics * Known current active malignant disease or in patient's history * Known immunodeficiency or HIV infection * Participation at another clinical trial within the last 6 months

What they're measuring

Reduction of a symptom score consisting of involved mucosal area and appearance of pain before and after treatment

Trial details

NCT IDNCT00130572

SponsorUniversity Hospital Tuebingen

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2007-12

View on ClinicalTrials.gov More Lichen Planus, Oral trials