Efficacy and Safety of a Retinoid for the Treatment of Severe Chronic Hand Dermatitis

Inclusion Criteria: * Chronic hand dermatitis, all types including hyperkeratotic, vesicular, fingertip dermatitis * Lasting for 6 months since initial diagnosis * Rated severe * Refractory to standard therapy including non-medicated therapy and avoidance of irritants and allergens * Refractory to topical steroids Exclusion Criteria: * Female patients who are pregnant or want to become pregnant * Female patients of child bearing potential who cannot use or will not commit to using two effective forms of contraception simultaneously * Patients whose disease is adequately controlled by standard non-medicated therapy and standard corticosteroid therapy