CompletedPhase 4

Japanese Primary Prevention of Atherosclerosis With Aspirin for Diabetes (JPAD) Trial

Japan2,539 participantsStarted 2002-12

Plain-language summary

The purpose of this study is to determine the effects of low-dose aspirin for the primary prevention of vascular events in patients with type 2 diabetes in Japan.

Who can participate

Age range

30 Years – 85 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients have type 2 diabetes mellitus (30 or more years old and 85 years old or less). * Patients give their informed consent to participate. Exclusion Criteria: * Patient has electrocardiographic changes, including ischemic ST-segment depression, ST-segment elevation, or pathologic Q waves. * Patient has fixed ischemic heart disease, utilizing coronary angiography. * Patient has cerebral vascular disease, including cerebral infarction, past hemorrhage, and experience of transient ischemic attack. * Patient has arteriosclerotic disease, which needs internal medicine and/or surgical medical treatment. * Patient has already taken the following anti-platelet or anti-thrombotic medicine: aspirin, ticlopidine, cilostazol, dipyridamole, trapidil, warfarin, and argatroban. * Patient has severe gastric and/or duodenal ulcer. * Patient has severe liver dysfunction. * Patient has severe renal dysfunction. * Patient has allergy for aspirin. * Patient has atrial fibrillation. * Pregnancy or the possible case of pregnancy.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Cardiovascular events

Timeframe: five years (median)

Cerebral vascular events

Timeframe: five years (median)

Aortic and peripheral vascular events, which needs internal medicine and/or surgical medical treatment

Timeframe: five years (median)

Trial details

NCT IDNCT00110448

SponsorKumamoto University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2008-04

View on ClinicalTrials.gov More Coronary Disease trials

Who can participate

Age range

30 Years – 85 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.